The UIC (Universal Index for Cirrhosis) index was created based on a study of 771 patients whose etiology of liver disease was: ETOH, NAFLD/NASH, HCV, HBV. Each patients’ stage of fibrosis per liver biopsy and laboratory values drawn near biopsy time were utilized to develop the index.
The need for more accurate and rapid identification of affected individuals was the nidus for the development of a readily available index which could be easily performed with available routine laboratory markers in patients with chronic liver disease due to all etiologies.
The novel UIC index was validated and superior in accuracy when compared to the presently available serological indices.